This symposium is designed for busy clinicians who desire to increase their declarative and procedural knowledge in the field of immune-mediated inflammatory diseases (IMIDs), as it applies to modern patient care. The first day of the symposium starts off with a “30,000-foot view” of immune responsiveness, followed by a series of recent advances in innate and adaptive immunity, as well as the immunologic implications of the microbiome. The afternoon session, “What is Hot?” takes a deep dive into the understanding of basic biochemistry/mechanisms of action of current and emerging biologic armamentarium that should improve understanding of clinical applications and predicting/preventing toxicity. The first day will also include a flipped classroom session, which allows participants to meet and discuss their toughest cases across the range of IMIDs and primary immunodeficiency disease with the faculty. The next day will include a session on the immunologic basis for wellness and how to apply it to clinical practice.

Also, on the agenda:

• Immune-Related Adverse Events from Cancer Immunotherapy
• Cases with the Masters: Vasculitis, Co-morbidities, Rheumatoid Arthritis, Psoriatic Arthritis, Spondyloarthritis and Beyond
• IL-17 and IL-12/ IL-23 – In Health and Disease
• Understanding B and T Cell Targeting in Autoimmune Diseases
• Targeting the IL-1 Family in Autoimmune and Autoinflammatory Diseases
• Human Behavior and Immunity – Slowing Our Aging?
• Talking to Patients about Anti-inflammatory Diets
• Diet and the Environment – Benefits of Plant-Based Diet
• Diet and Lifestyle in Psoriasis – Problems and Solutions
• Sorting Out Cardiovascular Risk in Autoimmune Diseases – Whose Job Is It?